[HTML][HTML] Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

A Inglis, R Ubungen, S Farooq, P Mata, J Thiam… - BMC genomics, 2021 - Springer
Obesity is a major risk factor for type 2 diabetes, and the … consist of catecholamines,
neuropeptides and also micro RNAs … gland loss of CHGB in knockout mice was shown to reduce …

Diabetes type 2 and kisspeptin: central and peripheral sex-specific actions

M Dudek, K Ziarniak, ML Cateau, L Dufourny… - Trends in Endocrinology …, 2019 - cell.com
… Finally, sex differences in body fat distribution exist that … negative feedback at the hypophyseal
and hypothalamic levels but … organs including fat, pancreas, stomach, and liver (Figure I). …

Sex differences in behavioral and metabolic effects of gene inactivation: The neuropeptide Y and Y receptors in the brain

C Eva, A Oberto, A Longo, P Palanza… - … & Biobehavioral Reviews, 2020 - Elsevier
… among the various strains of genetically modified mice and to … pancreatic polypeptides,
that includes peptide YY (PYY) and … /high fat diet (MHF) to male TgY1R/LacZ mice, increased …

[HTML][HTML] Murine models of obesity

T Martins, C Castro-Ribeiro, S Lemos, T Ferreira… - Obesities, 2022 - mdpi.com
… The Tsumura and Suzuki obesity and diabetes (TSOD) strain … of eating, such as the
neuropeptide Y and leptin, are also … with mild renal damage and increased pancreatic islet mass …

[图书][B] Origins and functions of the ventrolateral VMH: a complex neuronal cluster orchestrating sex differences in metabolism and behavior

WC Krause, HA Ingraham - 2017 - Springer
… of feedback loops in the hypothalamic-pituitary-gonadal axis. … -Cre mice, suggesting that this
neuropeptide might participate … -fat diet (HFD) at 10 weeks of age, whereas C57BL/6 mutant

[PDF][PDF] A guide for the design of pre-clinical studies on sex differences in metabolism

F Mauvais-Jarvis, AP Arnold, K Reue - Cell metabolism, 2017 - cell.com
… 2 diabetes and obesity show some degree of sex differences… behavior, like the loss of the
pituitary ability to mount a pre-… in neuronal firing, neuropeptide secretion, and autonomic …

Emerging roles for kisspeptin in metabolism

C Izzi‐Engbeaya, WS Dhillo - The Journal of Physiology, 2022 - Wiley Online Library
… Kisspeptin, a neuropeptide hormone, has been firmly … (including women, people with obesity
and people with diabetes). … A, Pancreas-specific kisspeptin receptor knockout mice develop …

Obesity, POMC, and POMC-processing enzymes: surprising results from animal models

I Lindberg, LD Fricker - Endocrinology, 2021 - academic.oup.com
… are not detected in mouse hypothalamus or pituitary, although a … Because PC1/3 and CPE
process many neuropeptide and … peptidergic differences between these 2 different pancreatic

[HTML][HTML] Sexual dimorphism in adipose-hypothalamic crosstalk and the contribution of aryl hydrocarbon receptor to regulate energy homeostasis

N Haque, SA Tischkau - International journal of molecular sciences, 2022 - mdpi.com
… Overall, this review summarizes sex differences in the … the pancreas circulate in the blood in
proportion to fat mass … CRH induces anorexia in the brain by inhibiting neuropeptide Y (NPY)…

[HTML][HTML] Kisspeptin and metabolism: the brain and beyond

M Dudek, K Ziarniak, JH Sliwowska - Frontiers in endocrinology, 2018 - frontiersin.org
Neuropeptide expression in KNDy neurons depends on the metabolic status. In chronically
obese female mice a … Kiss1r in the pancreas [mRNA and peptide (56)]. We have shown that …